Platinum
- Introduction
- Laboratory workflows: Optimize 32 manual steps
- Preanalytical errors at risk
- 3 second sample tube quality detection
- DxA 5000Fit error identification
- DxA 5000Fit is designed to automated step
- Best configuration to fit your laboratory
- More function, Less footprint
- Summary
Beckman Coulter Ltd. Beckman Coulter is committed to advancing healthcare for every person by applying the power of science, technology and the passion and creativity of our teams to enhance the diagnostic laboratory’s role in improving healthcare outcomes. Our diagnostic systems are used in complex biomedical testing, and are found in hospitals, reference laboratories and physician office settings around the globe. Beckman Coulter offers a unique combination of people, processes and solutions designed to elevate the performance of clinical laboratories and healthcare networks. We do this by accelerating care with a menu that matters, bringing the benefit of automation to all, delivering greater insights through clinical informatics and unlocking hidden value through performance partnership. An operating company of Danaher Corporation (NYSE: DHR) since 2011, Beckman Coulter is headquartered in Brea, Calif., and has more than 11,000 global associates working diligently to make the world a healthier place.
Early Detection of Sepsis Access PCT The Access PCT* assay is a procalcitonin blood test for laboratories supporting emergency departments and critical care settings. Use the capabilities of Access PCT to aid in the quantitative determination of procalcitonin levels. Access PCT offers state-of-the-art precision and low-end sensitivity for procalcitonin results you can trust. In addition, you can experience greater efficiency in your laboratory through workflow consolidation. Provide confidence in results and improve patient care through: >95% overall agreement with predicate method for accurate assessment of patients at risk of progression to severe sepsis and septic shock State-of-the art sensitivity and low-end precision―20% CV LoQ of 0.02 ng/mL and CV ≤8% at concentrations of ≥0.150 ng/mL Rapid access to results with first result in approximately 20 minutes Minimal sample draw of 35 µl pick-up volume Simplify sample processing and reduce separate PCT analysis workstation costs with: Random-access, high-throughput systems with >65 available assays and 50 reagent pack positions Fewer manual processing steps compared to standalone systems Onboard reagent storage of liquid, ready-to-use, 50-test reagent packs 42-day calibration stability Severity of infection biomarker, MDW Monocyte Distribution Width (MDW), proprietary to Beckman Coulter analyzers, is the regulatory-cleared hematological biomarker that helps to establish severity of infection and risk of sepsis in adult patients in the emergency department. MDW is a measure of increased morphological variability of monocytes in response to bacterial, viral or fungal infections. MDW is reported automatically as part of a routine CBC with Differential test on the DxH 900 and DxH 690T hematology analyzers using the Early Sepsis Indicator (ESId) application*, which enables automatic reporting with no workflow changes or need to order an additional test. MDW has been studied for the past decade with more than 16 peer-review publications and over 21,000+ patients1, confirming the robustness and reproducibility of MDW performance in different patient populations. MDW has cleared for FDA and acquired CE mark and Early Sepsis Indicator (ESId) application is required to see Monocyte Distribution Width(MDW) on DxH 900. 1. E. Piva et al., Monocyte Distribution Width (MDW) Parameter as a Sepsis Indicator in Intensive Care Units, Clin Chem Lab Med 2021. https://doi.org/10.1515/cclm-2021-0192 2. P. Hausfater et al., Monocyte Distribution Width (MDW) Performance as an Early Sepsis Indicator in the Emergency Department: Comparison with CRP and Procalcitonin in a Multicenter International European Prospective Study, Crit Care 2021; 25, 227. https://doi.org/10.1186/s13054-021-03622-5 3. A. Woo et al., Monocyte Distribution Width Compared with C-Reactive Protein and Procalcitonin for Early Sepsis Detection in the Emergency Department, PLoS ONE 2021; 16(4): e0250101. https://doi.org/10.1371/journal.pone.0250101 4. H. Lin et al., Clinical Impact of Monocyte Distribution Width and Neutrophil-to-Lymphocyte Ratio for Distinguishing COVID-19 and Influenza from Other Upper Respiratory Tract Infections: A Pilot Study, PLoS ONE 2020; 15(11): e0241262. https://doi.org/10.1371/journal.pone.0241262 5. L. Agnello et al., Monocyte Distribution Width (MDW) as a Screening Tool for Sepsis in the Emergency Department, Clin Chem Lab Med 2020; 58(11):1951-1957. https://doi:10.1515/cclm-2020-0417 6. G. Riva et al., Monocyte Distribution Width (MDW) as Novel Inflammatory Marker with Prognostic Significance in COVID 19 Patients, Scientific Report 2021; 11:12716. https://doi.org/10.1038/s41598-021-92236-6 7. Marcos-Morales, A et al., Elevated monocyte distribution width in trauma: An early cellular biomarker of organ dysfunction, Injury 2021; S0020-1383(21):00933-00935. https://doi.org/10.1016/j.injury.2021.11.026 8. E. Crouser et al., Monocyte Distribution Width: A Novel Indicator of Sepsis-2 and Sepsis-3 in High-Risk Emergency Department Patients, Critical Care Med 2019; 47:1018-1025. https://doi.org/10.1097/CCM.0000000000003799 9. E. Crouser et al., Improved Early Detection of Sepsis in the ED with a Novel Monocyte Distribution Width Biomarker, CHEST 2017; 152(3):518-526. https://doi.org/10.1016/j.chest.2017.05.039 10. A. Ognibene et al., Elevated Monocyte Distribution Width in COVID-19 Patients: The Contribution of the Novel Sepsis Indicator, Clinica Chimica Acta 2020; 509: 22-24. https://doi.org/10.1016/j.cca.2020.06.002 11. Malinovska, A et al., Monocyte distribution width as part of a broad pragmatic sepsis screen in the emergency department. JACEP Open. 2022; 3:e12679. https://doi.org/10.1002/emp2.12679
DxA 5000 Fit: Workflow Automation in a Compact - Laboratory workflows: Optimize 32 manual steps - Preanalytical errors at risk - 3 second sample tube quality detection - DxA 5000 Fit error identification - DxA 5000 Fit is designed to automated step - Best configuration to fit your laboratory - More function, Less footprint At a time when up to 75% of lab errors occur pre-analytically, analytical all laboratories could benefit from comprehensive workflow automation. That’s why we developed the DxA 5000 Fit, an automation system that offers a fundamentally improved approach to laboratory workflow by making intelligent automation accessible to labs of virtually any size. We expect that it is good opportunity to introduce Automation solution with optimized performance into the space. Wait for 3 SECONDS.
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